【摘要】 目的了解安徽省AIDS高流行县(区)通过积极的干预措施,对HIV与Mtb双重感染患者结核病治愈率和病死率的影响。方法收集分析安徽省AIDS高流行的7个县(区)2006年10月1日至2009年6月30日发现的199例Mtb与HIV双重感染患者抗结核疗程结束后的转归情况。结果Mtb与HIV双重感染患者中进行抗病毒治疗者135例,抗结核治疗者192例,181例接受了全程督导,疗程结束后1年内结核病治愈48例,完成疗程113例,迁出4例,死于结核病4例,死于非结核病21例,治疗失败1例,丢失1例。Mtb与HIV双重感染患者的治疗成功率为83.9%(161/192),总病死率13.0%(25/192),其中因结核病死亡率2.1%(4/192)。结论各级结核病防治机构与艾滋病防治机构合作,积极发现Mtb与HIV双重感染并进行及时的抗结核和抗病毒治疗,能有效提高Mtb与HIV双重感染患者的结核病治愈水平,降低病死率。更多还原

【Abstract】 Objective To understand the impact of active interventions on improving TB cure rate and reducing the fatality rate among Mtb/HIV co-infected patients in HIV high epidemic areas in Anhui province.Methods Information of the anti-TB treatment outcome of 199 Mtb/HIV co-infected patients registered from October 1 2006 to June 30 2009 in 7 high HIV epidemic counties was collected and analyzed.Results Among the 199 Mtb/HIV co-infected patients,135 cases received antiretroviral therapy,192 cases received anti-TB treatment and 181 cases accepted full course supervision.Within 1 year after the completion of anti-TB treatment,of co-infected patients 48 cases recovered from TB,113 cases completed the treatment course,4 cases were transferred out,4 cases died of TB,21 cases died of non-TB diseases,1 case failed and 1 case was lost.The treatment success rate of Mtb/HIV co-infected patients was 83.9%(161/192),the total fatality rate was 13.0%(25/192)while the fatality rate of TB was 2.1%(4/192).Conclusion The active cooperation between TB institutes and AIDS institutes of different levels would improve the detection of Mtb/HIV co-infected patients and provide timely diagnosis and treatment of both di-seases which could effectively increase the TB cure rate and reduce the fatality rate among Mtb/HIV co-infected patients.更多还原