【摘要】 目的分析重庆市2009年流感的流行特征,为制定防控策略提供科学依据。方法对重庆市流感病例进行描述性流行病学分析;监测哨点医院门诊流感样病例就诊比、病毒谱和优势毒株;监测流感样病例、急性呼吸道感染病例聚集和暴发疫情流行特征、病毒谱和流行毒株。结果 2009年,重庆市报告甲型H1N1流感病例3 178例,死亡2例,发病率为11.16/10万,死亡率为0.007/10万,病死率为0.06%;报告季节性流感11 708例,无死亡,发病率为41.24/10万。甲型H1N1l流感为2009年流感流行的优势毒株,在重庆的流行过程经历了输入个案病例、输入聚集性病例、病例本土化并出现多点聚集3个阶段,流行高峰为10月。病例分布于全市40个区县,主城区发病率高于远郊县。男︰女=1.35︰1,报告发病以10～20岁组最多,职业以学生为主。2009年11月和2010年1月两次人群甲型H1N1流感病毒血清抗体监测阳性率分别为15.40%和10.14%。结论 2009年重庆市发生了流感流行,疫情已出现本土化;学校是流感发病的重点场所,学生是罹患的重点人群;发现的病例为冰山一角,估计目前重庆市的感染人群在300～400万,病例在200万左右。更多还原

【Abstract】 OBJECTIVE To predict the morbidity tendency,and provide scientific evidence for its control told prevention in Chongqing according to the analysis of the epidemic situation of the A H1N1 flu in Chongqing from January to November in 2009.METHODS Using descriptive epidemiology analysis,we monitored the visit ratio,spectra and dominate strains of influenza virus among ILI(influenza-like illness)cases in OPC(out-patient clinic)of sentinel hospitals,and monitor the epidemic traits,spectra and dominate strains of influenza virus in ILI and ARI(acute respiratory infection)cases.RESULTS 3178 A H1N1 cases and 2 death cases were reported accumulatively in 2009.The IR(incidence rate)was 11.16/100 000,the mortality rate was 0.007/100 000 and the case fatality rate was 0.06%.For seasonal influence,11708 cases were reported and the IR was 41.24/100 000.The aH1N1 virus was the dominate strain and the epidemic process of aH1N1 flu in Chongqing experienced 3 stages:imported separate case,imported cluster,multipoint cluster and outbreak with domestic cases.The popular peak was in October.Patients were distributed in 40 districts/counties;IR in metropolitan area was higher than that in suburb.The of male to female was 1.35︰1;Most of the cases were students,and the proportion of 10-20 age group was the highest.The positive rate of H1N1 antibody in blood serum was 15.4% and 10.14% irrespectively in two surveillance.Conclusion There was a pandemic influenza in Chongqing in 2009 and the route of infection changed from importing into domestic.Schools are the key venues with high flu incidence,and students are the key prevalent group.Three to four millions flu infection and two millions flu cases were estimated in Chongqing.更多还原