急诊无创正压通气治疗尘肺合并慢性阻塞性肺疾病呼吸衰竭的临床研究

【摘要】 目的 分探讨无创正压通气（NPPV）在治疗尘肺合并呼吸衰竭（RF）中的临床疗效和成败预测的相关闲素。方法 将95例急诊就诊的各种原因引起RF的患者随机分为治疗组和对照组（ST组）,治疗组在ST组常规抗感染、化痰、解痉治疗的基础上给予NPPV,面罩连接呼吸机,通气模式采用压力支持通气（PSV）加呼气末正压通气（PEEP）。比较两组患者治疗前及治疗后2 h、1 d的呼吸频率、动脉血气变化、APACHEⅡ评分。结果 NPPV组治疗后2h、Id PaO₂/FiO₂、PaCO₂和pH与治疗前比较明显改善（P<0.05）,呼吸频率减慢（P<0.05）,APACHEII评分显著下降（P<0.05）。ST组治疗前后动脉血气、呼吸、APACHEⅡ评分均无显著变化（P>0.05）。结论 SNPPV技术是各种原因引起的RF非常重要的呼吸支持手段。更多还原

【Abstract】 Objective To study curative effect and successful or failure forecast fator of noninvasive positive pressure ventilation（NPPV）in the treatment of COPD of respiratory failure（RF）. Methods 95 patients with RF caused by pneumoconiosis were divided at random into standard medicaltherapy alone（control group）and standard medical therapy plus NPPV（treatment group）,Standard medical therapy included anti-infection.eliminating sputum,spasmolysis,The patients accepted NPPV by aface mask connected to a ventilator set in pressure support ventilation（PSV）and positive end-expiratory pressure（PEEP）,The respiratory rate,heart rate,arterial blood gas,APACHE 1 I score of two groups at admission and Off 2 hours,1 day after NPPV were compared. Results In NPPV group,there were significant improvement in PaO₂,FiO₂,PaCO₂,pH and RR,on the 2 hours,1 day after therapy（P<0.05）. APACHEII score was statistically decreased after therapy（P<0.05）.Conclusion NPPV is all important respiratory support method for RF induced by many reasons.更多还原