【摘要】 目的分析脑电图及事件相关电位(P300)对于急性一氧化碳中毒后迟发性脑病(DEACMP)的临床意义。方法对2005—2010年在安阳市人民医院神经内科住院的40例DEACMP患者及36例急性一氧化碳中毒(AC-MP)未发生迟发脑病患者的相关因素及电生理进行分析比较。结果 DEACMP患者的年龄、昏迷时间、高压氧治疗持续时间与ACMP患者比较,差异均有统计学意义(P<0.05)。DEACMP组脑电图轻、中、重度异常与ACMP组比较,差异有统计学意义(P<0.05),脑电图中、重度异常患者发生DEACMP较多。DEACMP组P300潜伏期及波幅与AC-MP组比较,差异均有统计学意义(P<0.05)。结论脑电图及P300对DEACMP的发生及判定预后有重要意义。更多还原

【Abstract】 Objective To analyze the clinical significance of electroencephalogram and event related potentials in delayed encephalopathy after acute carbon monoxide poisoning(DEACMP).Methods Related factors and electrophysiology of 40 DEACMP patients and 36 ACMP patients without delayed encephalopathy admitted to the Department of Neurology of Anyang People′s Hospital from 2005 to 2010 were analyzed and compared.Results The age,coma duration and hyperbaric time of the DEACMP patients showed statistically significant differences compared with those of the ACMP patients(P<0.05).The mild,moderate and severe abnormalities in the DEACMP group showed statistically significant differences compared with those of the ACMP group(P<0.05).Patients with severely abnormal electroencephalogram showed a higher incidence of DEACMP.The incubation and amplitude of P300 in DEACMP group showed statistically significant differences compared with those of the ACMP group(P<0.05).Conclusion The electroencephalogram and event related potential have important significance in the occurrence and prognosis of DEACMP.更多还原