【摘要】 目的:研究PTEN在子宫内膜癌中的表达。方法:应用免疫组化法检测60例子宫内膜癌中PTEN的表达情况。结果:60例子宫内膜癌中,PTEN失表达率为66.7%(40/60),34例增生期子宫内膜中,PTEN失表达率为35.3%(12/34)。结论:子宫内膜癌与PTNE缺失有关,PTEN蛋白的缺失可能在子宫内膜癌的发生中具有一定的作用。更多还原

【Abstract】 Objective: To study the expression of PTEN in endometrioid adenocarcinoma(EC).Methods:The expression of PTEN in 60 cases of endometrioid adenocarcinoma by immunohistochemistry.Results:The positive expression rates of PTEN at 60 patients with endometrioid adenocarcinoma was 66.7%(40/60),The positive expression rates of PTEN at 34 patients with endometrial hyperplasia was 35.3%(12/34).Conclusion:The positive expression of PTEN and endometrioid adenocarcinoma is closely correlation,PTEN play an important role in endometrioid adenocarcinoma.更多还原