【摘要】 目的检测动脉粥样硬化脑梗死(ACI)患者及健康体检者血浆脂蛋白相关磷脂酶A2(Lp-PLA2)水平,探讨颈动脉斑块稳定性与血浆Lp-PLA2水平相关性。方法采用双抗体夹心酶联免疫吸附法(ELISA)检测血浆Lp-PLA2水平,同时检测血脂、纤维蛋白原等生化指标;行颈动脉彩色多普勒超声检查,评估颈动脉斑块稳定性。结果不稳定斑块组血浆Lp-PLA2水平明显高于稳定斑块组(P<0.01)。结论血浆Lp-PLA2水平可作为颈动脉斑块稳定性的预测指标。更多还原

【Abstract】 Objective To observe the levels of plasma lipoprotein-associated phospholipase A2(Lp-PLA2) in atherosclerotic cerebral infarction and healther people,analysis of plasma Lp-PLA2 levels with carotid artery plaque stability.Methods Plasma Lp-PLA2 levels were detected by enzyme linked immunosorbent assay(ELISA),and the levels of blood lipids and fibrinogen,The carotid plaque stability were determined by cervical vascular color Dopplerultrasound.Rseults As compared to the vulnerable plaque group,the levels of plasma lipoprotein-associated phospholipase A2(Lp-PLA2) were higher in stable plaque group(P<0.01).Conclusion Lp-PLA2 serves as a predictive indicator of carotid artery plaque stability.更多还原