【摘要】 目的:了解原发性干燥综合征(pSS)患者皮肤黏膜表现,提高诊疗水平。方法:对59例pSS患者的临床资料进行回顾性分析。结果:59例pSS患者中,21例有皮肤黏膜表现,发生率为35.6%,其中表现为紫癜、瘀斑8例(38.1%),口腔溃疡4例(19.0%),皮肤干燥3例(14.3%),下肢红斑结节4例(19.0%),雷诺现象2例(9.5%)。结论:pSS的皮肤黏膜表现并不少见,可能使患者直接到皮肤科就诊,所以皮肤科医生应了解pSS的相关知识并予以重视,这有助于pSS早期诊断,避免误诊和漏诊。更多还原

【Abstract】 Objective:To delineate the mucocutaneous manifestations of primary Sjogren’s syndrome(pSS) and improve its the diagnosis and treatment.Methods:The clinical data on 59 patients with pSS were analyzed retrospectively.Results:Among the 59 patients,twenty-one(36.6%) were found to have mucocutaneous manifestations including purpura and petechiae in 8 cases (38.1%),oral ulcers in 4 cases(19.0%),dry skin in 3 patients(14.3%),erythemas and nodules on lower extremities in 4 cases (19.0%),Raynaud’s phenomenon in 2 cases(9.5%).Conclusion:Mucocutaneous manifestations in pSS are not rare.Patients could visit dermatology clinics.Dermatologists should pay attention to and have the relevant knowledge of pSS,which could help early diagnosis and avoid misdiagnosis and missed diagnosis of pSS.更多还原