【摘要】 目的:通过术前检测肝胆管结石病患者肝脏功能储备,评估肝切除术的手术风险。方法:回顾性分析134例因原发性肝胆管结石病行肝切除术患者的临床资料,根据术前肝脏储备功能评估方式分为吲哚氰绿组(ICG组)和Child-Pugh评分组(CP组)。比较两组患者术前、术中参数以及术后并发症发生率。结果:ICG组术后肝功能衰竭发生率(0.16%,1/64)明显低于CP组(12.85%,9/70;P<0.05)。ICG组术后总并发症发生率明显低于CP组(18.75%vs37.14%,P<0.05)。结论:吲哚氰绿排泄试验比Child-Pugh评分系统能更有效地评估患者肝储备功能,利于筛选手术患者,减少肝切除术后肝功能衰竭及其他手术并发症,提高手术安全性。更多还原

【Abstract】 Objective: To evaluate the risk of hepatectomy by detecting liver functional reserve preoperatively for patients with primary hepatolithiasis. Methods: The clinical data of 134 patients with primary hepatolithiasis who underwent hepatectomy were reviewed.In terms of evaluation methods for preoperative liver functional reserve they were divided into a Child-Pugh group(group CP) and an indocyanine green group(group ICG).The preoperative and intraoperative parameters,and the incidence of postoperative complications were analyzed. Results: Liver failure was more common in group CP(12.85%) than that in group ICG(1.56%,P<0.05).The overall complication rate in group CP(37.14%) was higher than in group ICG(18.75%,P<0.05). Conclusion: ICG15 retention test is more accurate in evaluating liver functional reserve than Child-Pugh scoring system.It may predict the postoperative liver failure in patients with primary hepatolithiasis undergoing hepatectomy,decrease postoperative complications,and increase operation safety.更多还原