【摘要】 目的了解随州市2010年手足口病流行病学和病原学特征,为手足口病防控提供科学依据。方法统计分析随州市2010年的手足口病例发病报告数据,对所有重症病例、所辖县市每月随机抽取的5例轻症病例采样进行病原学检测分析。结果 2010年随州市共报5 284例手足病病例,全年均有发病,3～5月发病较多,主要为4岁以下儿童,5～7月报告11例重症病例;125例病例病原学检测,EV 71阳性19例,阳性率为15.2%;Cox A 16阳性25例,阳性率为20.0%,PE阳性15例,阳性率为12%,1～4月检出的手足口病原体为Cox A 16,8～12月检出的病原体为EV 71,5～7月Cox A 16和EV 71均有检出。结论随州市2010年手足口病发病主要在春夏季,4岁以下儿童,病原体上半年以Cox A 16为主,下半年以EV 71为主,引起死亡和重症的病原体为EV 71,提示重点人群是4岁以下EV 71感染病例。更多还原

【Abstract】 Objective To analyze the characteristics of the epidemiology and etiology of Hand-Foot-Mouth Disease(HFMD) in Suizhou in 2010,and provide basis for further prevention and control of HFMD.Methods Data of reported HFMD case were analyzed,for all the severe cases and 5 mild cases randomly selected from the relevant cities/counties monthly,pathogen samples were examined.Results A total of 5 284 cases reported in 2010,Most cases was reported on March-MAY,aged under 4 years old child,11 severe cases reported in May-July.In 125 tested samples,EV71 positive were 19,which accounted for 15.2%,and Cox A16 positive were 25,which accounted for 20%,and PE positive were 15,which accounted for 12%,Cox A16 was detected as only the HFMD pathogens on Jan.-April,EV71 was on Aug-Dec,and both on others months EV71 was the pathogen of case with severe syndrome or death case.Conclusions HFMD was epidemic on mainly late spring and summer in 2010 in Suizhou,involved in young child age under 4.The major causative agents were EV71 and Cox A16,pathogen of EV71 was the main reason to cause death and severe,and onset time was mainly concentrated in the 5-7 month.更多还原