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法舒地尔治疗蛛网膜下腔出血患者的临床研究

Clinical study of Fashudier treatment on the patients with subarachnoid hemorrhage

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【作者】 林松梅高文陈尊玲

【Author】 LIN Song-mei,GAO Wen,CHEN Zhun-ling.Jiaozhou Central Hospital,Qingdao 266300,China

【机构】 青岛市胶州中心医院

【摘要】 目的观察法舒地尔注射液治疗蛛网膜下腔出血后脑血管痉挛的疗效和安全性。方法选择在本院住院的蛛网膜下腔出血患者67例,随机分为两组,观察组34例,对照组33例,两组患者均在常规治疗的基础上,观察组给予法舒地尔注射液治疗,对照组给予尼莫地平注射液治疗,疗程15d,疗程结束后比较两组患者的临床表现、病情变化、意识的改善、血压及Hunt & Hess分级等指标。结果两组患者在疗程结束后,总有效率比较差异有统计学意义,观察组的疗效明显优于对照组(P<0.05),观察组的不良反应发生率低于对照组。结论治疗蛛网膜下腔出血后脑血管痉挛,法舒地尔注射液是一种较尼莫地平同样安全而疗效更好的药物。

【Abstract】 Objective To observe the efficacy and safety of Fashudier injection treatment of cerebral vasospasm after subarachnoid hemorrhage.Methods 67 patients in our hospital with subarachnoid hemorrhage were randomly divided into two groups,34 patients in observation group,33 cases in control group,all patients in two groups were on the basis of conventional therapy,the observation group were given Fashudier injection,the control group received Nimodipine injection treatment course of 15 days,two groups were compared after treatment of clinical manifestations,the condition changes,the improvement of consciousness,blood pressure and other indicators of Hunt & Hess grade.Results The patients at the end of treatment,the total effective rate was statistically significant difference between the observed group significantly better than the control group(P<0.05),observation of adverse reactions was lower than the control group.Conclusion The treatment of cerebral vasospasm after subarachnoid hemorrhage,injection of fasudil is a relatively safe and efficacy of nimodipine as better drugs.

  • 【文献出处】 中国实用医药 ,China Practical Medicine , 编辑部邮箱 ,2011年21期
  • 【分类号】R743.3
  • 【被引频次】1
  • 【下载频次】71
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