【摘要】 目的分析2008-2010年产气肠杆菌分离株的临床分布及耐药性特点,为临床医师诊断和治疗提供依据。方法对2008-2010年住院患者各类标本分离到的产气肠杆菌,进行标本分布和耐药性回顾性统计分析。结果 3年内共分离出产气肠杆菌570株,主要来源于痰334株,占58.6%、尿液121株,占21.2%和血液32株,占5.6%,主要分布在呼吸内科220株,占38.6%、ICU 174株,占30.5%和神经外科42株,占7.4%;药敏结果显示,对氨苄西林、头孢噻肟、头孢西丁、头孢唑林、头孢呋辛酯及头孢呋辛钠耐药率均>50.0%,对阿米卡星、庆大霉素、亚胺培南和美罗培南有较好的敏感性。结论产气肠杆菌多为多药耐药,临床医师应根据药敏结果合理选择抗菌药物,以延缓产气肠杆菌耐药性的产生。更多还原

【Abstract】 OBJECTIVE To investigate the clinical distribution and drug resistance of Enterobacter aerogenes from 2008 to 2010 to provide the scientific evidence for clinical diagnosis and treatment. METHODS The distribution and drug resistance of E.aerogenes isolated from 2008 to 2010 were analyzed retrospectively. RESULTS Totally 570 strains of E.aerogenes were mainly isolated from sputum(334 strains),urine(121 strains) and blood(32 strains),accounting for 58.6%,21.2% and 5.6%,respectively.The drug resistant rates to ampicillin,cefotaxim,cefoxitin,cefazolin,cefuroxime sodium,cefuroxime were more than 50.0%.A1l isolates of E.aerogenes distributed in many departments were more sensitive to carbapenem,amikacin and gentamicin. CONCLUSION E.aerogenes clinical strains are mostly multidrug-resistant.Rational use of antibiotics is important for the containment of the resistance of E.aerogenes.更多还原