【摘要】 目的探讨溶血性葡萄球菌医院感染危险因素。方法采用1∶1配对病例对照研究方法,于2010年3～5月调查福建省某综合性三级甲等医院2008年1月至2010年1月各病区发生溶血性葡萄球菌医院感染的住院患者及其对照组共98对。结果多因素分析显示,APACHE-II评分(OR:6.06,95%CI:1.75～20.97)、应用β-内酰胺类+酶复合制剂(OR:9.61,95%CI:2.34～39.55)、气管插管(OR:9.53,95%CI:1.54～58.97)、留置鼻饲管(OR:11.53,95%CI:2.17～61.20)为溶血性葡萄球菌医院感染的独立危险因素。结论留置导管要切实做到无菌操作,尽量缩短留置时间,合理使用抗菌药物等措施将有利于降低溶血性葡萄球菌医院感染的发病率。更多还原

【Abstract】 Objective To explore the risk factors of nosocomial infections caused by Staphylococcus haemolyticus.Methods A 1∶1 matched case-control study was carried out in a Fujian provincial hospital in 2010.The risk factors of Staphylococcus haemolyticus infections were analyzed for hospitalized patients.Results A total of 98 Staphylococcus haemolyticus infection cases were matched with controls.A multivariate analysis showed that APACHE-II ratings(OR:6.06,95%CI:1.75~20.97),the medication of beta-lactams and beta-lactamase inhibitors(OR: 9.61,95%CI:2.34~39.55),endotracheal intubation(OR:9.53,95%CI:1.54~58.97) and indwelling feeding tube(OR:11.53,95%CI:2.17~61.20) were independent risk factors of nosocomial infections of Staphylococcus haemolyticus.Conclusion Aseptic catheterization,rational use of antibiotics and immune inhibitors can decrease nosocomial infection incidences caused by Staphylococcus haemolyticus.更多还原