【摘要】 本研究旨在探讨"鹅-鱼"生产体系中水体细菌滋长及所造成的内毒素(LPS)对鹅生长性能和免疫机能的影响。试验1比较了不同水面载鹅密度种鹅血液LPS浓度及所产雏鹅的生长性能。高密度鹅群的血液LPS浓度极显著高于正常密度鹅群(P<0.01),且所产种蛋受精率和孵化率均低于正常密度鹅群。孵化第25天死胚蛋、弱胚蛋尿囊液中LPS浓度极显著高于活胚蛋(P<0.01)。此外,高密度鹅群所产雏鹅的死亡率较高,早期采食量低且生长性能差,肉鹅胸肌率、腿肌率均显著低于正常密度鹅群(P<0.05),而腹脂率和皮下脂肪率则显著高于后者(P<0.05)。试验2观察外源LPS对雏鹅采食和生长的影响。对雏鹅腹腔注射外源LPS显著降低了采食量、生长速度和屠宰性能(P<0.05),并导致肝脏和脾脏肿大。试验3观察了LPS对鹅免疫机能的影响。对生长鹅注射外源LPS使鹅血液中的白细胞数量迅速下降且极显著低于对照组(P<0.01)。LPS还严重降低免疫BSA后抗BSA抗体的效价。以上结果说明LPS通过降低鹅的免疫机能影响其健康状况;降低采食量,导致雏鹅生长和屠宰性能下降。更多还原

【Abstract】 This study investigated the effects of lipolyshaccharide (LPS),the endotoxine released after death of the pathogenic bacteria,on performance growth and immune functions in meat geese. Experiment 1 compared the LPS concentrations in blood of goose flocks with different stocking density on water,and growth performances of their goslings. LPS concentrations in geese blood were higher in the high density flock than in low (ones P<0.01),and the latter had lower egg fertility and hatchability than the former flock. In addition,LPS concentration in allantoic fluid was the highest in dead,inferior embryos than that in normal embryos at 25th day. Furthermore,goslings produced by the high density flock showed higher mortality,lower feed intake and growth rate at the early stage of growth. These goslings also had more abdominal and subcutaneous fat than that of those produced by standard density flock geese (P<0.05). Experiment 2 compared feed intake and growth performances of goslings after challenge with exogenous LPS. Peritoneal administrations of exogenous LPS reduced feed intake and growth rate,carcass quality (P<0.05),and especially made liver and spleen swell. In experiment 3,administration of exogenous LPS to growing goslings reduced significantly the numbers of leukocytes in blood (P<0.01). LPS treatment also significantly reduced the antibody titre against bovine serum albumin (P<0.01). The above results illustrated that LPS impaired gosling immune function,reduced feed intake,growth performances and carcass quality.更多还原