【摘要】 目的:探讨口服铁剂改善孕期贫血及铁储备状态的作用。方法:选择144例妊娠贫血孕妇(贫血组,口服多糖铁复合物胶囊150 mg/次,2次/天)、100例正常孕妇(预防组,口服多糖铁复合物胶囊150 mg/次,1次/天)和50例正常孕妇(对照组,膳食补铁),测定血红蛋白(Hb)、红细胞计数(RBC)、血清铁蛋白(SF)、血清铁(SI)。结果:贫血组和预防组Hb和RBC呈现早-中期下降(P<0.05)、中-晚期上升(P<0.05)的变化,对照组各孕周Hb、RBC呈逐渐下降趋势(P<0.05)。整个孕周3组孕妇SF均呈进行性下降(P<0.01)。3组孕妇SI早-中期下降较为明显(P<0.01)。结论:单纯膳食补铁不能满足孕期对铁的需求。孕期铁储备处于持续消耗状态。需重视孕早期及孕中期铁剂补充。更多还原

【Abstract】 Objective:To explore the improving effect of oral iron on pregnant women with iron-deficiency anemia(IDA) and iron storage status. Methods:144 pregnant women with IDA(anemia group,treated with oral administration of polysaccharide-iron complex capsules,150 mg per time,twice a day),100 normal pregnant women(prevention group,treated with oral administration of polysaccharide-iron complex capsules,150 mg per time,once a day) and 50 normal pregnant women(control group,treated with dietary supplementation) were selected.The levels of hemoglobin,red blood cell count,serum ferritin and serum iron were measured. Results:The levels of hemoglobin and red blood cells decreased at early to middle period(P<0.05),then increased at middle to late period in anemia group and prevention group(P<0.05).In control group,the levels of hemoglobin and red blood cells showed a gradual-decreasing trend at different gestational weeks(P<0.05).The level of serum ferritin decreased gradually in the whole gestational age in the three groups(P<0.01).The decrease of serum iron at early to middle period was obvious in the three groups(P<0.01). Conclusion:Simple dietary supplementation can’t satisfy the iron requirement during pregnancy.Iron storage during pregnancy is in a continuous consumption state,more attention should be paid to iron supplementation during the first and second trimester of pregnancy.更多还原