【摘要】 目的:探讨子宫内膜异位症腹腔镜保守手术后不同延续用药对预后的影响。方法:腹腔镜下子宫内膜异位症保守手术的Ⅲ期、Ⅳ期子宫内膜异位症患者160例。其中A组43例,术后不用药;B组53例,术后加用促性腺激素释放激素激动剂(GnRH-a)治疗(曲普瑞林);C组64例,术后加用短效避孕药炔雌醇环丙孕酮(达英-35)。比较3组患者术后症状缓解率、复发率及受孕率。结果:3组的术后2年症状缓解率无统计学差异(P>0.05);B、C组的复发率低于A组(P<0.05),B组的复发率低于C组(P<0.05);B、C组的受孕率高于A组(P<0.05)。结论:中重度子宫内膜异位症腹腔镜手术治疗后加用曲普瑞林或达英-35巩固治疗,能降低复发率并提高受孕率,且曲普瑞林的疗效优于达英-35。更多还原

【Abstract】 Objective:To explore the effect of different continure medication on prognosis after laparoscope conservative operation of endometriosis.Methods:The postoperative women were divided into 3 groups:35 without endocrinal therapy(group A),43 treated with gonadotropin releasing hormone agonist(GnRH-a)(3.75 mg,once every 28 d,group B),51 treated with Diane-35(1 tablets every day,group C).The remission rate,recurrent rate and incidence of adverse drug reactions were compared.Results:The postoperational 2 year symptom alleviation rate among 3 groups had no significance(P>0.05).The recurrence rate of Group B and C was lower than that in Group A(P<0.05),but that of Group B was lower than that of Group C(P<0.05),the conception rate of Group B and C was higher than that of Group A(P<0.05).Conclusion:Laparoscope conservative postoperation combined triptorelin or Diane-35 in moderate and severe endometriosis could consolidate therapeutic effect,reduce recurrent and conception rate,and triptorelin has the better effect than Diane-35.更多还原