【摘要】 目的:探讨蒙古族细菌性阴道病妇女与健康妇女阴道乳杆菌属内乳杆菌分布种类及产生过氧化氢(H2O2)能力的差异。方法:以102例蒙古族BV患者为病例组,98例正常蒙古族妇女为对照组,检查阴道乳酸杆菌菌种分布,测定阴道乳酸杆菌产H2O2能力及鉴定阴道内乳杆菌种类。结果:两组乳酸杆菌检出率分别为21.6%(22/102)、75.5%(74/98),两组比较差异有统计学意义(χ2=21.016,P=0.001);两组乳酸杆菌菌种分布差异无统计学意义(P>0.05),均以卷曲乳杆菌、加氏乳杆菌、嗜酸乳杆菌和干酪乳杆菌为优势菌;H2O2阳性乳酸杆菌分离率分别为27.3%(6/22)、75.7%(56/74),两者相比差异有统计学意义(χ2=4.528,P<0.050)。结论:蒙古族BV患者与蒙古族健康妇女相比阴道乳杆菌检出率明显下降;阴道产过氧化氢乳杆菌分离率及整体产过氧化氢能力显著下降;蒙古族BV患者与正常蒙古族妇女阴道乳杆菌种分布相似。更多还原

【Abstract】 Objective:To explore the differences of vaginal lactobacillus species distribution and producing H2O2 ability between the women of mongol nationality with bacterial vaginosis and healthy women of mongol nationality. Methods:102 women of mongol nationality with bacterial vaginosis were selected as case group,98 normal women of mongol nationality were selected as control group,the distribution of vaginal lactobacillus species was examined;the producing H2O2 ability of vaginal lactobacillus was detected,the vaginal lactobacillus species were determined. Results:The detection rates of lactobacillus in the two groups were 21.6%(22/102) and 75.5%(74/98),respectively,there was significant difference between the two groups(χ2=21.016,P=0.001).There was no significant difference in distribution of lactobacillus species between the two groups(P>0.05).Lactobacillus crispatus,lactobacillus gasseri,lactobacillus acidophilus and lactobacillus casei were the main species;the isolation rates of lactobacillus with positive H2O2 in the two groups were 27.3%(6/22) and 75.7%(56/74),respectively,there was significant difference between the two groups(χ2=4.528,P<0.05). Conclusion:Compared with healthy women of mongol nationality,the detection rate of vaginal lactobacillus in the women of mongol nationality with bacterial vaginosis decreases significantly;the isolation rate of vaginal lactobacillus producing H2O2 and the total ability of producing H2O2 decrease significantly;the distributions of vaginal lactobacillus species of the women of mongol nationality with bacterial vaginosis and healthy women of mongol nationality are similar.更多还原