【摘要】 目的探索血清锌浓度水平是否与重症患者预后、ICU滞留时间、序贯器官衰竭估计(SOFA)评分等相关。方法纳入2009年1～3月进入ICU所有患者(年龄≥18岁)。记录患者人口学特征、ICU滞留时间、预后以及行SOFA评分。进入ICU 24h内采血检测锌浓度、C反应蛋白和蛋白浓度。结果共纳入36例患者。血锌和SOFA评分呈负相关。SOFA评分≥8血锌浓度明显低于SOFA评分<8的患者。结论在器官功能衰竭和重症患者中,血锌浓度明显下降,适量补充锌可能有助于患者恢复。更多还原

【Abstract】 Objective To investigate the hypothesis that a reduction in serum zinc levels among critically-ill patients is related to prognosis,length of stay in the ICU,sequential organ failure assessment(SOFA) scores.Methods This study included all the patients(age≥18 years) entered ICU from January 2009 to March 2009.Patients’ demographic features,SOFA scores,survival status,length of ICU stay were collected.Blood samples were collected within 24 hours after admission and analyzed for serum zinc,C-reactive protein and albumin levels.Results Total of 36 patients was included.Serum zinc concentrations were inversely correlated with SOFA scores.Patients with SOFA scores ≥8 had significantly lower serum zinc concentration compared with patients with SOFA scores <8.Conclusion Serum zinc concentrations were decreased in organ failure and critical illness.Administration of zinc may be helpful for critically ill patients.更多还原