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吸烟与中年人颈动脉粥样硬化的剂量-反应关系探讨

The Dose-response Relationship between Cigarette Smoking and Carotid Atherosclerosis in Middle-aged People

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【作者】 崔永生申明慧田艳萍

【Author】 CUI Yongsheng1,2 SHEN Minghui1,2 TIAN Yanping1 1.The First People’s Hospital of Kaifeng,Kaifeng 475000,China;2.Kaifeng Key Laboratory for Clinical Medicine,Kaifeng 475000,China

【机构】 开封市第一人民医院开封市临床医学重点实验室

【摘要】 目的探讨中年人吸烟与颈动脉粥样硬化的关系。方法选择308例研究对象,进行问卷调查、实验室检查和颈动脉超声检查。结果吸烟组颈动脉斑块形成的人数明显高于不吸烟组,差异有高度统计学意义(P<0.01);吸烟者颈动脉斑块形成的例数随着吸烟指数的增加而增多,趋势性检验具有统计学意义(P<0.01)。结论吸烟可增加中年人颈动脉粥样硬化的风险,且存在一定的剂量-反应关系。

【Abstract】 Objective To examine the relationship between cigarette smoking and carotid atherosclerosis in middle-aged people.Methods 308 cases were selected and data were collected by questionnaire,laboratory tests and carotid arteries ultrasound measurements.Results The number of plaque of carotid artery person in smoking group was higher than non-smoking group(P<0.01);the number of carotid plaque person was increased with smoking index,and the trend test was significant(P<0.01).Conclusion Cigarette smoking could increase the risk of carotid atherosclerosis in middle-aged people and some dose-response relationship was existed.

  • 【文献出处】 中国现代医生 ,China Modern Doctor , 编辑部邮箱 ,2011年19期
  • 【分类号】R543.4
  • 【被引频次】17
  • 【下载频次】166
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