【摘要】 [目的]探讨社会支持对阿尔茨海默病(AD)发生的影响,为进一步探明AD的病因和制订预防策略奠定基础。[方法]采用以社区人群为基础的成组病例对照研究,对可能影响AD发生的社会支持相关因素进行分析。资料分析采用非条件Logistic回归分析方法,先进行单因素分析,然后再进行多因素分析。[结果]在控制了年龄和受教育程度后,与配偶和子女共同居住的老年人患AD的危险性最低(OR=0.14,95%CI:0.03～0.67),其次是丧偶与子女居住的老年人(OR=0.30,95%CI:0.12～0.79),与配偶居住的老年人(OR=0.35,95%CI:0.14～0.85);家人尊重和有子女者可能是AD的保护性因素(OR=0.40,95%CI:0.17～0.95;OR=0.17,95%CI:0.03～0.89);独自在家的频率≥2次/周者患AD的危险性明显增多(OR=2.37,95%CI:1.10～5.09)。[结论]AD的发生和发展与老年人的社会支持状况有关。调动有效的社会支持来源,尽可能地让老年人获得帮助与支持,有助于预防AD的发生。更多还原

【Abstract】 [Objective]To investigate the relationship between social support and Alzheimer’s disease(AD)among the elderly in community of Guiyang.[Methods]By using a case-control study based on a population in community,the effect of social support on AD was analyzed.A non-conditional logistic regression was used in data analysis.[Results]After adjusting for age and education,it was showed that the lowest risk of AD was existed in the elderly living with their partners and their children(OR=0.14,95%CI:0.03-0.67),and then the widow living with their children,and with their partners(OR=0.30,95%CI:0.12-0.79;OR=0.35,95%CI:0.14-0.85).Respect perceived from the family members and having children might have protective effects on AD(OR=0.40,95%CI:0.17-0.95;OR=0.17,95% CI:0.03-0.89).The elderly who lived alone over 2 times per week showed a higher risk for AD(OR=2.37,95%CI=1.10-5.09).[Conclusion]Social support plays an important role in the development of AD.It will be helpful to prevention of AD through providing effective social support for the elderly.更多还原