【摘要】 磁共振显像具有安全性能高、特异性较高、时间和空间分辨率高等优点,且可进行活体无创检查,已经在多个领域的细胞移植示踪中取得了初步成功。磁共振是肝/干细胞移植的最佳示踪工具。MR对比剂能增加磁共振示踪的效果,MR对比剂主要有两类:即超顺磁性对比剂和顺磁性对比剂。SPIO和Gd-BOPTA是这两类的典型代表。SPIO和Gd-BOPTA在肝/干细胞移植中均有应用,从它们的理化特性、标记方法、安全性、磁化特性和成像序列等方面进行比较,各具优点及缺点。更多还原

【Abstract】 Magnetic resonance imaging is with the advantages of high safety,high specificity,time and spatial resolution beside non-invasive examination in vivo.Cell transplantation has achieved initial success in multiple areas of the tracer.MRI is The best tracer of hepatocyte/stem cell transplantation.MR contrast agent can increase the effects of magnetic resonance tracer.There are two types of MR contrast agents: Superparamagnetic contrast agent and magnetic contrast agent.SPIO and Gd-BOPTA are typical representative of these two categories to have been used for hepatocyte/stem cell transplantation.The properties,labeling,safety,magnetic properties and imaging sequences,etc.of MRI were discussed.更多还原