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6种光稳定剂对那他霉素抗光解的影响

Effects of Six Light Stabilizers on Natamycin Anti-photolysis

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【作者】 卢向阳; 刘伟成; 卢彩鸽; 杨剑芳; 田兆丰; 刘霆; 董丹; 张涛涛;

【Author】 LU Xiang-yang,LIU Wei-cheng,LU Cai-ge,YANG Jian-fang,TIAN Zhao-feng,LIU Ting,DONG Dan,ZHANG Tao-tao(Institute of Plant & Enviromental Protection,Beijing Academy of Agricultural and Forestry Science,Beijing 100097,China)

【机构】 北京市农林科学院植物保护环境保护研究所;

【摘要】 [目的]那他霉素作为抗真菌剂具有广谱、高效、安全、不易获得抗性的优点,但其在紫外光下容易降解的弱点限制了它在田间的应用,通过添加光稳定剂可提高它的光稳定性。[方法]以水为药剂和光稳定剂的载体,采用抑菌圈法和盆栽法测定光稳定剂对药剂稳定性的影响。[结果]紫外吸收剂UV-234、UV-531、UV-1164和光屏蔽剂SiO2有抑制那他霉素光解的作用,其中紫外吸收剂的效果优于SiO2,在一定时间内可显著抑制光解;自由基捕获剂T-123和抗氧剂1010没有任何作用;30 mg/L那他霉素分别与3种紫外吸收剂(3 g/L)混用防治番茄灰霉病的效果可达72.9%~78.1%,而单用30 g/L那他霉素的防效仅为35.2%。[结论]适宜的紫外吸收剂可显著提高那他霉素的光稳定性,提高防治番茄灰霉病的效果。

【Abstract】 [Aims]Natamycin(NT) possess advantages of broad-spectrum antifungal properties,high efficiency,safe to humans and animals and long time antimicrobial characteristics,but its use in the fi eld is impeded by susceptibility to light-induced degradation.Adding the light stabilizers can improve its photostability.[Methods]The effect of light stabilizers on NA photostability were determined using inhibition zone assays and pot experiments and the water as carriers.[Results]UV absorbers(UV-234,UV-531,UV-1164) and UV shielding agent SiO2 can inhibit the photolysis of NT.Effi cacies of the UV absorbers are better than that of SiO2,and they could signifi cantly inhibit the photolysis within a certain period of irradiation.Free radical scavenger T-123 and antioxidant 1010 have no effect.The pot experiments showed that NA applied at 30 mg/L with UV absorber at 3 g/L controll Botrytis cinerea by 72.9-78.1%,compared with NA applied alone by 35.2%.[Conclusions]Suitable UV absorbers for NA can improve its light stability and increase its control of B.cinerea.

【基金】 北京市科技计划资助项目(D0706005040231)
  • 【文献出处】 农药 ,Agrochemicals , 编辑部邮箱 ,2011年08期
  • 【分类号】TQ450.1
  • 【被引频次】13
  • 【下载频次】271
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