【摘要】 目的:探讨妊娠期高血压疾病患者脐动脉S/D与血清一氧化氮(NO)的相关性。方法:选取接受生产的产妇90例,其中患有妊娠期高血压疾病患者40例,分别对两组患者运用血清NO测定,采用硝酸还原酶法测定了分娩前外周血血清NO的含量,以及运用彩色多普勒超声检测患者子宫动脉以及脐动脉血流阻力指标S/D值。结果:妊娠期高血压疾病患者产前外周血血清NO含量较正常产妇组患者低(P<0.05)。而且对周血血清NO含量与脐动脉S/D值的相关性研究中,妊娠高血压患者呈负相关性(P<0.05)。结论:NO的合成减少可能是导致妊娠期高血压疾病的发病有关,而且NO合成减少可能与胎盘循环阻力增高有一定的联系。更多还原

【Abstract】 Objective To investigate patients with hypertensive disorder complicating pregnancy umbilical artery S/D and serum nitric oxide(NO)relevance.Methods 90 cases of maternal acceptance production,including 40 patients with pregnancy-induced hypertension,respectively,two groups were determined by serum-0 determined by nitrate reductase before delivery NO content in blood serum,and the use of color Doppler ultrasonography in patients with uterine artery resistance index and umbilical artery S/D value.Results Peripheral blood of patients with gestational hypertension result of prenatal maternal serum NO levels in patients than the normal lower(P<0.05).But also on peripheral blood NO levels in serum and umbilical artery S/D values of the correlation study,pregnancy-induced hypertension in patients with negative correlation(P<0.05).Conclusion The reduction of NO synthesis may lead to the pathogenesis of gestational hypertension,and decreased NO synthesis may be related to increased placental vascular resistance have some contact.更多还原