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食管贲门癌患者术后空腹血糖水平异常升高不利于术后恢复

The elevated fasting palsma glucose level is not conducive to postoperative recovery in patients with esophageal and cardiac cancer

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【作者】 郑庆锋姚震旦李少雷吴楠陈晋峰张力建杨跃

【Author】 ZHENG Qing-feng,YAO Zhen-dan,LI Shao-lei,WU Nan,CHEN Jin-feng,ZHANG Li-jian,YANG YueThoracic Surgery Ⅱ,Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education),Peking UniversitySchool of Oncology,Beijing Cancer Hospital & Institute,Beijing 100142,China)

【机构】 北京大学临床肿瘤学院北京肿瘤医院北京市肿瘤防治研究所恶性肿瘤发病机制及转化研究教育部重点实验室胸外二科

【摘要】 目的研究食管贲门癌患者术后空腹血糖水平异常升高与术后恢复的关系。方法根据1996年1月~2009年10月在北京大学临床肿瘤学院胸外二科手术治疗的196例食管贲门癌患者,分别就术前、术后空腹血糖水平记录以及术后并发症记录,采用χ2检验对数据进行分析。结果 (1)食管贲门癌患者术后空腹血糖水平升高的患者明显多于术前,分别为115例及38例;(2)患者术前血糖空腹水平的升高与术后并发症的发生无统计学关联;(3)术后空腹血糖水平升高的患者,术后严重感染及吻合口瘘发生率明显升高(P<0.05,P<0.01)。结论食管贲门癌患者术后空腹血糖水平异常升高不利于术后恢复,术后有效控制空腹血糖可能促进患者术后恢复。

【Abstract】 Objective To study the relation of elevated fasting plasma glucose level after surgical operation and postoperative recovery in patients with esophageal and cardiac cancer.Methods From January 1996 to October 2009,196 cases of surgical treatment in the thoracic surgery II of Peking University School of Oncology were recruited,observing and recording fasting plasma glucose levels before and after operation and postoperative complications.χ2 test was used to analyze the data.Results(1)The patients with elevated fasting glucose levels after operation were significantly more than those before operation;(2)No significant correlation was found between elevated fasting plasma glucose levels in preoperative patients and postoperative complications;(3) In postoperative patients with elevated fasting glucose levels,the incidence of postoperative severe infection and anastomotic leakage was significantly higher(P<0.05,P<0.01).Conclusion The elevated fasting plasma glucose level in the patients of esophageal and cardiac cancer after operation is not conducive to postoperative recovery.The effective control of postoperative fasting plasma glucose to normal levels may facilitate to patients recovery.

  • 【文献出处】 基础医学与临床 ,Basic & Clinical Medicine , 编辑部邮箱 ,2011年03期
  • 【分类号】R735
  • 【被引频次】2
  • 【下载频次】77
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