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生长因子对牙髓干细胞的矿化作用

Growth factors in promoting the mineralization of dental pulp stem cells

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【作者】 吕陶红高燕

【Author】 Lü Taohong,Gao Yan.(Dept.of Conservative Dentistry and Endodontics,Hospital of Stomatology,Guanghua School of Stomatology,Sun Yat-Sen University,Guangzhou 510055,China)

【机构】 中山大学光华口腔医学院·附属口腔医院牙体牙髓病科

【摘要】 健康牙髓中含有的具有多向分化、高效增殖和自我更新潜能的牙髓干细胞,在牙髓损伤后牙本质修复再生和牙/骨组织工程中具有至关重要的作用。本文就牙髓干细胞的矿化潜能、生长因子及其在促牙髓干细胞矿化和作用机制方面的研究进展作一综述。

【Abstract】 Stem cells in the healthy dental pulp possess multi-lineage differentiation capability,high proliferation rate and self-renewal capability,which are recognized being vital to the dentin regeneration after injuries and tooth/bone tissue engineering.Growth factors are a kind of cell factors that stimulate the growth activities of cells.This review is aimed at elaborating the role and mechanism of growth factors in promoting the mineralization of dental pulp stem cells.

  • 【文献出处】 国际口腔医学杂志 ,International Journal of Stomatology , 编辑部邮箱 ,2011年05期
  • 【分类号】R780.2
  • 【被引频次】1
  • 【下载频次】219
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