【摘要】 目的探讨缺血性脑血管疾病的血流动力学变化及其影响因素。方法对2007年7月～2009年7月住院的40例缺血性脑血管病患者的DSA和CTPI结果进行回顾性分析,了解脑血管狭窄程度、部位及侧支循环建立情况与血流动力学变化的关系,以指导治疗方案的制定。结果 CTPI分期与颅外动脉不同狭窄程度不具有相关性(r=0.081,P=0.57),与颅内动脉不同狭窄程度之间亦不具有相关性(r=0.007,P=0.951);侧支循环分级对CTPI分期的影响具有统计学差异(P<0.05);侧支循环类型对CTPI分期的影响不具有统计学差异(P>0.05)。结论联合DSA与CTPI,可以综合评估脑血管形态与血流动力学变化,为临床治疗方案的制定提供依据。更多还原

【Abstract】 Objective To approach the hemodynamic changes of ischemic cerebrovascular diseases and its influencing factors.Methods With the 40 patients’ results of digital subtraction angiography(DSA) and computed tomography perfusion imaging(CTPI),the relationships between the degree/location of cerebrovascular stenosis and the hemodynamic changes were analyzed to guide the formation of therapeutic regimens.Results There was no correlation between the different stages of CTPI and different degrees of stenosis of extracerebral(r=0.08,P=0.57) and intracerebral(r=0.007,P=0.951) artery stenosises;The different gradings of collateral circulation had statistically significant effect with the stage of CTPI,P<0.05;and the different types of collateral circulation had no statistically significant effect with the stage of CTPI,P>0.05.Conclusions To combine the DSA and CTPI,we can evaluate the cerebrovascular morphous and the hemodynamic changes comprehensively and provide informations for formalating the therapeutic regimens.更多还原