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名老中医经验方芙蓉膏体外抗炎作用实验研究

The experimental study on the in vitro anti-inflammatory effect of the furong ointment

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【作者】 张琦于庆生潘晋方帅剑锋吴生兵刘举达

【Author】 Zhang Qi,Yu Qingsheng,Pan Jinfang,et al Department of general surgery,the First Hospital Affiliated to Anhui college of Traditional Chinese Medicine,Hefei 230031,China

【机构】 安徽中医学院第一附属医院普外科安徽中医学院实验中心

【摘要】 目的观察芙蓉膏对炎症模型动物的抗炎作用,为临床应用提供实验依据。方法通过二甲苯致小鼠耳廓肿胀度实验、大鼠角叉菜胶致足趾肿胀度实验、小鼠棉球肉芽肿增生实验观察芙蓉膏的抗炎作用。结果芙蓉膏能显著抑制二甲苯致小鼠耳廓肿胀,明显减轻角叉菜胶性致大鼠足跖肿胀度,并具有显著抑制棉球诱发所致小鼠炎症的肉芽增生作用,与模型组比较差异有统计学意义(P<0.05),抗炎作用强于阳性药物(金黄散)对照组。结论芙蓉膏外用给药,对急性炎症反应与慢性炎症反应具有明显的抑制作用,说明芙蓉膏具有明显的抗炎作用。

【Abstract】 Objective To study the effect of Furong Ointment for inhibiting inflammation in animal model,and provide experimental basis for clinical application.Methods The anti-inflammatory action was studied through xylene-induced mouse auricle swelling experiment,carrageena-induced mouse paw swelling experiment and cotton ball-induced granuloma proliferation.Results The Furong Ointment inhibited obviously xylene-induced mouse auricleswelling and carrageena-induced rat paw swelling and the cotton ball-induced granuloma proliferation,there were significant differences compared with the model group(P<0.05),the therapeutic effect of the Furong Ointment was better than the positive control group(Jin huang San).Conclusion Fu-rong Paste has a significant anti-inflammatory effect as a drug for external use

【基金】 安徽中医学院临床科研基金(项目编号:2009LC-035B)
  • 【文献出处】 安徽医学 ,Anhui Medical Journal , 编辑部邮箱 ,2011年11期
  • 【分类号】R285.5
  • 【被引频次】24
  • 【下载频次】334
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