【摘要】 目的:观察养肝化瘀法治疗HBsAg阳性肿瘤患者化疗肝损害的临床疗效。方法:确诊为恶性肿瘤并接受化疗、出现肝功能损害的患者78例,随机分为治疗组40例与对照组38例,治疗组在常规西医保肝治疗的基础上加用中药养肝化瘀剂口服,比较两组患者治疗前后的临床症状体征、血清肝功能指标、患者KPS评分情况。结果:治疗组肝功能改善总有效率为87.5%,对照组为65.8%,对比显示治疗组在改善患者症状体征、降低血清转氨酶、胆红素,升高白球蛋白比例、提高患者KPS评分情况方面均优于对照组,差异具有显著性(P<0.05)。结论:养肝化瘀法能有效治疗HBsAg阳性肿瘤患者化疗所致的肝损害。更多还原

【Abstract】 Objective:To observe the clinical effect of Nourishing-Liver-Removing-blood-stasis Chinese medicine in treating HBsAg positive cancer patients with chemotherapy drugs-induced liver injury.Methods:78 HBsAg positive cancer patients with chemotherapy drugs-induced liver injury were divided into treatment group and control group. Besides routine hepatoprotective treatment,the treatment group was treated with Chinese medicine. The clinical manifestation,serum biochemical test,and Karnofsky(KPS)were compared between the two groups.Results:The total effective rate of the treatment group was 87.5% and that of the control group was 65.8%,and there were obvious differences between the two groups in clinical manifestation,serum biochemical test,and Karnofsky’s score.Conclusion:Nourishing-Liver-Removing-blood-stasis Chinese medicine has the function of preventing and treating HBsAg positive cancer patients with chemotherapy drugs-induced liver injury.更多还原