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脑梗死患者血清叶酸和维生素B12水平的测定及其临床意义

The relationship and the clinical significance between the serum folate and vitaminB12 levels in patients with cerebral infarction

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【作者】 李兴华赵云芳付艳

【Author】 LI Xing-hua1,ZHAO Yun-fang1,FU Yan2.(1.The Second Affiliated Hospital of Xinjiang Medical University,Xinjiang Urumchi 830065,China;2.The first Affiliated Hospital of Xinjiang Medical University)

【机构】 新疆医科大学第二附属医院新疆医科大学第一附属医院

【摘要】 目的探讨血清叶酸、维生素B12与脑梗死的关系及其临床意义。方法采用电化学发光免疫分析技术测定45例脑梗死患者和50例健康人血清叶酸、维生素B12的水平。结果急性脑梗死患者血清叶酸、维生素B12水平明显低于对照组(P<0.001,0.05),重型患者血清叶酸、维生素B12水平明显低于中型及轻型患者(P<0.01,0.01)。结论血清叶酸、维生素B12水平降低与脑梗死的发生有关,可能是其中又一危险因子。

【Abstract】 Objective To study the relationship and the significance between the serum levels of folate and vitamin B12 with cerebral infarction.Methods The levels of folate and viamin B12 in serum samples of 45 patients with cerebral infarction and 50 healthy people were determined by electro-chemiluminescence immunoassay.Results The levels of folate and vitamin B12 in serum of patients with acute cerebral infarction group were significantly lower than healthy people(P<0.001,0.05).In severe patients,the folate levels decreased significantly(P<0.01,0.01) as compared with middle and mild types.Conclusion The low serum folate and vitamin B12 were associated with the cerebral infarction,it maybe one of the risk factors for cerebral infarction.

【关键词】 叶酸维生素B12脑梗死
【Key words】 FolateVitamin B12Cerebral infarction
  • 【文献出处】 中国实验诊断学 ,Chinese Journal of Laboratory Diagnosis , 编辑部邮箱 ,2010年03期
  • 【分类号】R743.33
  • 【被引频次】13
  • 【下载频次】134
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