【摘要】 目的:探讨中药寒热药性与水溶性糖的相关性,进一步阐明中药四性与物质基础的关系。方法:选取10种寒性中药和10种热性中药,提取水溶性糖,分别加入盐酸羟胺、吡啶和乙酸酐进行乙酰化反应,测定水溶性糖的GC/MS指纹图谱,利用Fisher方法建立判别函数,分析实验结果。结果:Fisher判别函数实现了对20种中药寒热药性的准确识别,组内回代一致率为100%。结论:Fisher可以作为判别中药寒热药性与水溶性糖关系的统计学工具,水溶性糖是中药寒热药性的物质基础之一。更多还原

【Abstract】 Objecive:To discuss the relationship between water-soluble sugar and cold-heat properties and further reveal correlations of four properties and material basis.Method:Water-soluble sugars were purified from 10 herbs with cold properties and 10 herbs with heat properties.After acetylation,GC /MS fingerprints of water-soluble sugars were determined and the results were analyzed by Fisher.Result:Discriminant function had been established by Fisher.The Fisher discriminant analysis could distinguish the cold and heat properties between 20 herbs that the back substitution in group was 100%.There was difference between the drugs with cold and heat properties in the GC /MS fingerprints,which corresponded to the different water-soluble sugars in the cold and heat herbs.Conclusion:The Fisher analysis could differentiate the herbs with cold and heat properties,and it was an effective statistical tool to study the relationship between the cold and heat properties by water-soluble sugar.It concludes that the water-soluble sugar is one of the material basis of four properties of herbs.更多还原