【摘要】 目的探讨吡喹酮规范与安全性应用模式的血防效果。方法在血吸虫病流行区选择3个流行村,采用规范性与安全性的化疗对策,每年选择恰当的治疗时间,因病施药,对不同的人群给予不同的化疗方案。结果规范性与安全性的化疗措施在3个试点村实施3年后,化疗覆盖率由试点前的77.45%上升到99.79%,居民感染率由试点前的3.16%下降至2.08%,吡喹酮的不良反应发生率由10.65%降至0.63%。结论在血吸虫病流行区规范性与安全性使用吡喹酮,有利于控制传染源,也是提高化疗质量、化疗覆盖率,降低居民感染率和吡喹酮的不良反应发生率的新举措。更多还原

【Abstract】 Objective To study the effects of schistosomiasis control by means of standardized and safe use of praziquantel.Methods Three villages in schistosome-endemic areas were selected as study sites.Strategies for standardized and safe use of chemotherapy,such as selecting appropriate times for treatment each year,treating the disease with medication,and tailoring strategies to different patients,were studied.Results Three years after measures for standardized and safe use of chemotherapy were carried out in the three affected villages,chemotherapy coverage increased from 77.45% to 99.79%,the infection rate among residents decreased from 3.16% to 2.08%,and side effects of praziquantel decreased from 10.65% to 0.63%.Conclusion The standardized and safe use of praziquantel in affected areas is a new measure to help control sources of infection,improve the quality and coverage of chemotherapy,and reduce the infection rate among residents and adverse reactions to praziquantel.更多还原