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乌鲁木齐地区淋球菌、沙眼衣原体、溶脲脲原体感染情况调查

Detection and analysis of Neisseria gonorrhoeae,Chlamydia trachomatis and Ureaplasma urealyticum infection in patients with urogenital tract infections in Urumqi,China

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【作者】 阿曼古丽.牙生李翠玲刘晓兰王红英田为真王灵庞楠楠马秀敏

【Author】 AMANGULI Yashen1,LI Cui-lin2,LIU Xiao-lan3,4,WANG Hong-ying4,TIAN Wei-zhen4,WANG Ling4,PANG Nan-nan4,MA Xiu-min4(1.First Teaching Hospital of Xinjiang Medical University,Urumqi 830054,China;2.Department of Gynaecology,People’ s Hospital of Xinjiang Uygur Autonomous Region;3.Department of Gynaecology,People’ s Hospital of Shihezi City;4.College of Basic Medicine,Xinjiang Medical University)

【机构】 新疆医科大学第一附属医院检验科新疆维吾尔自治区人民医院妇科石河子市人民医院妇科新疆医科大学基础医学院

【摘要】 目的分析新疆乌鲁木齐地区淋球菌(Neisseria gonorrhoeae,NG)、溶脲脲原体(Ureaplasma urealyticum,UU)和沙眼衣原体(Chlamydiatrachomatis,CT)的感染情况。方法运用荧光定量PCR对乌鲁木齐地区316例疑似淋菌性/或非淋菌性尿道炎患者NG、CT和UU感染情况进行检测。结果 316例受检者NG感染率为21.2%,CT感染率为16.5%,UU感染率为24.7%,NG、CT、UU合计感染率为62.3%。男女、汉族和维吾尔族患者民族间NG、UU和CT感染率差异无统计学意义(P>0.05)。结论乌鲁木齐地区泌尿生殖道感染门诊患者中NG、CT和UU感染率较高;在检测NG、CT和UU方面,荧光定量PCR简便、快速,敏感性高、特异性强。

【Abstract】 Objective To detect and analyze urogenital tract infections of Neisseria gonorrhoeae(NG),Chlamydia trachomatis(CT) and Ureaplasma urealyticum(UU) in Urumqi.Methods Three hundred and sixteen specimens from patients with a urogenital tract infection were tested for NG,CT,and UU using fluorescent quantitative PCR(FQ-PCR).Results The overall rate of infection was 62.3%;the rate of infection with NG,CT,and UU was 21.2%(67/316),16.5%(52/316),and 24.7%(78/316),respectively.There were no significant differences in the rate of NG,CT,and UU infection among the genders and the Uygur and Han ethnic groups.Conclusion Patients with urogenital tract infections in Urumqi had a high rate of infection with NG,CT,and UU.The FQ-PCR assay is easy to perform,quick,and able to detect NG,CT,and UU in urogenital tract infections with a high level of sensitivity and specificity.

【基金】 教育部课题(No.Z2005-1-65003)
  • 【文献出处】 中国病原生物学杂志 ,Journal of Pathogen Biology , 编辑部邮箱 ,2010年06期
  • 【分类号】R759
  • 【被引频次】5
  • 【下载频次】68
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