【摘要】 目的分析阑尾炎性分泌物中病原菌的分布及药物敏感性,为临床经验合理选择抗菌药物提供参考。方法对医院627例阑尾炎患者的分泌物标本进行细菌培养和药物敏感性试验,并进行统计分析。结果 627例阑尾炎性分泌物标本中检出病原菌358例,阳性率为57.10%,共检出病原菌24种、421株,主要以革兰阴性杆菌为主,占94.54%;排前3位病原菌依次为大肠埃希菌(61.52%)、铜绿假单胞菌(10.93%)、肺炎克雷伯菌(8.31%);大肠埃希菌对哌拉西林/他唑巴坦、阿米卡星敏感率分别为95.37%、96.14%,对亚胺培南、美罗培南敏感率为100.00%。结论大肠埃希菌为阑尾炎的主要致病菌,临床应加强病原菌的检测和药物敏感性试验,减少耐药菌株的产生。更多还原

【Abstract】 OBJECTIVE To analyze the disposition and drug sensitivity of pathogenic bacteria in appendicitis extcretions,and to choose appropriate antibiotics in accordance with experimental results.METHODS Germ culture,as well as susceptibilities test were performed in 627 cases of appendicitis,and the statistic analysis was conducted.RESULTS Out of appendicitis excretions specimens of 627 cases,358 cases were detected out the positive rate 57.10%,there were 24 species,421 strains,the major of them were Gram-negative bacilli,accounting for 94.54% including Escherichia coli(61.52%) Pseudomonas aeruginosa(10.93%) and Klebsiella pneumoniae(8.31%).The sensitive rates of E.coli to piperacillin/tazobactam,amikacin,meropenem and imipenem were 95.37%,96.14% 100% and 100%,respectively.CONCLUSION E.coli is the main pathogen in appendicitis,detection and susceptibility test of pathogenic bacteria in clinics should be strengthened to prevent the occurrence of the drug resistant strain.更多还原