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针灸对结肠癌肝转移患者外周血T淋巴细胞亚群和NK细胞活性的影响

Effect of acupuncture on the activity of the peripheral blood T lymphocyte subsets and NK cells in patients with colorectal cancer liver metastasis

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【作者】 赵昌林彭磷基张子丽张涛李恒谋

【Author】 ZHAO Chang-lin~1,PENG Lin-ji~1,ZHANG Zi-li~2,ZHANG Tao~1,LI Heng-mou~1(1.Department of Oncology, 2.Acupuncture Department,Qifu Affiliated Hospital of Guangzhou TCM University,Guangzhou 511495,China)

【机构】 广州中医药大学祈福医院肿瘤科广州中医药大学祈福医院针灸科

【摘要】 目的:研究针灸对结肠癌肝转移患者免疫功能的影响。方法:60例经病理和影像学诊断明确的结肠癌肝转移患者,采用针灸治疗。针刺取足三里、三阴交、内关、上巨虚、合谷、太溪、太冲、阴陵泉、阳陵泉等穴位;艾灸取神阙、关元、气海、足三里穴。在治疗前后用流式细胞仪检测CD3、CD4、CD8 T细胞和自然杀伤(NK)细胞的数量变化。结果:治疗后T细胞亚群CD3、CD4、CD8和NK细胞的数量变化较治疗前均有明显的升高,具有统计学意义。结论:针灸可以提高结肠癌肝转移病人的免疫功能。

【Abstract】 Objective To study the effect of acupuncture on the immune function of patients with colorectal cancer liver metastasis.Methods Sixty cases with colorectal cancer liver metastasis confirmed by pathology and ma-geology diagnosis were treated with acupuncture.Zusanli(ST 36),Sanyinjiao(SP 6),Neiguan(PC 6),Shangjuxu (ST 37),Hegu(LI 4),Taixi(KI 3),Taichong(LR 3),Yinlingquan(SP 9),Yanglingquan(GB 34),etc.were selected for acupuncture,and Shenque(CV 8),Guanyuan(CV 4),Qihai(CV 6),Zusanli(ST 36) were selected for moxibustion.The changes of CD3,CD4,CD8 T cells and NK cells in value were examined with flow cytometry before and after treatment.Results The value of T lymphocyte subsets such as CD3,CD4 and CD8,as well as NK cells were obviously increased after treatment,and there were significant differences between them before and after treatment.Conclusion Acupuncture can improve the immune function of patients with colorectal cancer liver metastasis.

【基金】 广东省中医药管理局基金资助项目:050098
  • 【文献出处】 中国针灸 ,Chinese Acupuncture & Moxibustion , 编辑部邮箱 ,2010年01期
  • 【分类号】R246.1
  • 【被引频次】90
  • 【下载频次】839
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