【摘要】 目的了解慢性腹痛患儿幽门螺杆菌(H.pylori)的感染状态及幽门螺杆菌感染患儿内镜下表现的特点。方法应用C13尿素呼气试验,对905例以慢性腹痛为主要症状的患儿进行检测,对C13呼气试验阳性者进行电子胃镜检查。结果905例慢性腹痛患儿中H.pylori呈阳性185例(20.44%),随年龄增长,其H.pylori阳性率升高,学年组已达高峰。对H.pylori阳性者进行胃镜检查结果显示十二指肠隆起病变47例占25.40%,结节性胃炎41例占22.1%,慢性浅表性`胃炎38例占20.5%,结节性胃炎伴十二指肠隆起病变23例占12.43%,十二指肠球部溃疡23例占12.4%。胃溃疡7例,占3.7%(其中包括1例复合性溃疡),结节性胃炎伴十二指肠炎6例,占3.2%。结论H.pylori感染为小儿慢性腹痛的主要原因之一,也是导致慢性胃炎及消化性溃疡的主要原因之一。C13尿素呼气试验方便,快速,无痛苦,无放射性,是一较好的H.pylori检测方法;对既有消化道症状同时C13呼气试验阳性者进行胃镜检查能够协助临床诊断及治疗。更多还原

【Abstract】 Objective To understand the infection of Helicobacter pylori(H.pylori) in children with chronic abdominal pain and its endoscopic features.Method C13 urea breath test was applied to 905 cases of children with chronic abdominal pain as the main symptom.Electronic endonscopy was used to children whose C13 breath test result was positive.Result Among the 905 cases,185 cases were H.pylori-positive(20.44%),with the positive rate increasing along with age and reaching peak value at school age.The endoscopy showed there were 47(25.40%) cases of duodenal elevated lesions,41(22.1%) cases of nodular gastritis,38(20.5%) cases of chronic superficial gastritis,23(12.43%) cases of nodular gastritis with duodenal elevated lesions,23(12.4%) cases of duodenal ulcer.7(3.7%) cases of gastric ulcer(including 1 case of complex ulcer),and 6(3.2%) cases of nodular gastritis with duodenitis.Conclusion H.pylori infection is one of the main causes of chronic abdominal pain in children,which also leads to chronic gastritis and peptic ulcer.C13 breath test is an easy,fast,painless and non-radioactive way to detect H.pylori.Endoscopy can assist in clinical diagnosis and treatment of patients with both gastrointestinal symptoms and positive C13 breath test result.更多还原