节点文献

乌蕨总黄酮体外抗氧化活性的研究

Antioxidant Activity of Flavonoids from Stenoloma chusanum(L). Ching in vitro

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 吴晓宁余陈欢徐静红

【Author】 WU Xiao-ning1,2,YU Chen-huan1,XU Jing-hong2(1. School of Pharmacy ,Zhejiang Chinese Medical Univeisity,Hangzhou 310053,China;2. Department of Pharmacy ,Zhejiang Medical College ,Hangzhou 310053,China)

【机构】 浙江中医药大学药学院浙江医学高等专科学校药学系

【摘要】 目的研究乌蕨总黄酮体外抗氧化活性。方法采用分光光度法,测定乌蕨总黄酮对羟自由基、脂质过氧化的清除能力、总还原力和总抗氧化作用,并通过多元线性回归分析,考察了乌蕨总黄酮含量及其体外抗氧化活性的相关性。结果乌蕨总黄酮具有较强的抗氧化性能、自由基清除能力和一定的还原力,可有效抑制脂质过氧化,且抗氧化作用与乌蕨总黄酮含量呈正相关。结论乌蕨总黄酮具有显著的抗氧化活性,黄酮类化合物可能是其抗氧化作用的主要物质基础。

【Abstract】 Objective To investigate the antioxidant activity of flavonoids from Stenoloma chusanum (L.) Ching in vitro. Methods The radical scavenging,total antioxidant and reducing capacity of hydroxy radicals and lipid peroxides by the total flavonoids from Stenoloma chusanum(L.)Ching were detected and analyzed by using spectrophotometry and multiple linear regression analysis. The correlation between contents of total flavonoids and their antioxidant activity in vitro was surveyed. Results The extracts showed strong antioxidant activities,free radical clearance and some reduction ability,by efficiently inhibiting lipid peroxidation in a dose dependent manner. Conclusion The total flavonoids may be the main active component of Stenoloma chusanum (L.) Ching which exerting an antioxidative activity.

  • 【文献出处】 医药导报 ,Herald of Medicine , 编辑部邮箱 ,2010年03期
  • 【分类号】R285.5
  • 【被引频次】34
  • 【下载频次】638
节点文献中: