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缺血性脑损伤的神经保护治疗研究进展

Neuroprotective Treatment for Ischemic Injury

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【作者】 柏华; 魏岗之;

【Author】 BAI Hua1,WEI Gang-zhi2.(1.Department of Neurology,the First Affiliated Hospital of Chengdu Medical College in Sichuan Province,Chengdu 610500,China;2.Department of Neurology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China)

【机构】 成都医学院第一附属医院神经内科; 首都医科大学宣武医院神经内科;

【摘要】 分析总结最近几年国际上神经保护治疗研究的进展和临床应用前景,侧重于脑缺血方面的研究成果。首先是关于针对N-甲基-D-门冬氨酸受体和阻断谷氨酸神经毒性的研究;其次是关于寻找体内正常生理生化物质或其他有效成分的替代物用于脑梗死的治疗;随后介绍了将生物工程的新成果和新技术运用于脑梗死实验研究的新动向;最后讨论了上述研究成果在临床治疗中实际操作的可能性。

【Abstract】 The progress and prospect for clinical application of the neuroprotective treatment on the international research in recent years are summarized in this review,focusing on research achievement on cerebral infarction and cerebral ischemia.The first part focuses on the N-methyl-D-aspartic acid receptor and blocking glutamate neurotoxicity studies,the second part concerns the search for normal physiological and biochemical material or other active ingredient alternative for the treatment of cerebral infarction,and then we introduce the new trends with the new achievements and technology in biological engineering for experimental research in cerebral infarction,and finally we discuss the practice possibilities for clinical operation with the research results above.

  • 【文献出处】 医学综述 ,Medical Recapitulate , 编辑部邮箱 ,2010年06期
  • 【分类号】R743.3
  • 【被引频次】7
  • 【下载频次】349
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