【摘要】 [目的]采用320排动态容积冠状动脉CT血管成像(CCTA)探讨冠状动脉病变程度与左心室形态及功能的关系。[方法]采用320排动态容积CT对180例胸闷原因患者进行心电门控宽探测器平台下非螺旋全器官容积增强扫描,分别按冠状动脉病变狭窄程度分级和冠状动脉病变范围分为不同组别,并对各组左心室形态及功能指标进行统计学分析。[结果]与正常对照组比较,舒张功能指标在冠状动脉病变不同狭窄程度分级组和不同病变分支范围组均有下降(P﹤0.05),左心室射血分数(LVEF)仅重度狭窄组与正常对照组有明显差异,而与冠状动脉病变范围无明显关系。左心室形态指标中,不同狭窄程度分级组和不同病变分支范围组左房舒张末期内径(LADD)、室间隔厚度(IVST)、左室后壁厚度(LVPWT)与正常对照组比较有明显差异(P﹤0.05),而左室舒张末期内径(LVDD)只与冠状动脉病变程度相关,与病变分支范围无明显关系。[结论]320排冠状动脉CTA对评价冠状动脉病变有一定的临床价值,左心室舒张功能和左心室形态与冠心病病变程度密切相关,左心室收缩功能与病变狭窄程度有关,与病变范围无关。更多还原

【Abstract】 [Objective]To evaluate the relationship between left ventricular morphology,function and severity of coronary artery lesions with 320 slice dynamic volume coronary CT angiography.[Methods]Used 320 slice dynamic volume CT to scan 180 patients with chest pain.The patients were divided into different groups respectively according to the disease degrees and the number of diseased vessels.Compared heart structure and function among different groups.[Results]Compared to the normal control group,significant differences in the LADD,IVST,LVPWT and E/A(P﹤0.05),the change of LVEF were found only in high degree stenosis.There was no significant difference in LVEF and LVDD among patients with single branch,double branches and three branches lesion.[Conclusion]The 320 slice coronary CT angiography has good clinical value in assessing coronary artery stenosis.Left ventricular morphology and diastolic function correlate closely with severity of coronary artery lesions,left ventricular systolic function only related the degree stenosis.更多还原