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乳腺癌患者围手术期凝血功能的变化

Investigation of perioperative hemostatic alterations in patients with breast cancer

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【作者】 杨晓民; 任宏; 邓智平; 宋张骏; 李逢生; 马冬梅;

【Author】 YANG Xiao-min1,2,REN-Hong1,DENG Zhi-ping2,SONG Zhang-jun2,LI Feng-sheng2,MA Dong-mei1 1The First Affiliated Hospital,Medicine School,Xi’an Jiaotong University,Xi’an 710061,China;2Department of Gynecology Oncology,Shaanxi Province Tumor Hospital,Xi’an 710061,China.

【机构】 西安交通大学医学院第一附属医院; 陕西省肿瘤医院;

【摘要】 目的:研究乳腺癌术后患者血液凝血功能的变化。方法:随机选出50名(ASAⅠ-Ⅱ级)乳腺癌患者,分别测定手术前后凝血系列(FIB,TT,PT,APTT,ALT)。结果:乳腺癌患者术后FIB明显高于术前(P<0.05),APTT明显低于术前(P<0.05),PLT较术前增高(P<0.05)。结论:乳腺癌术后患者血液呈高凝状态,因而术后存在深部静脉血栓和肺栓塞的危险,及时预防治疗具有重要临床意义。

【Abstract】 Objective:To invest the change of perioperative hemostatic alterations in patients with breast cancer.Methods: To test the serial of perioperative hemostatic alterations(FIB,TT,PT,APTT,PLT)in 50 breast cancer patients(ASAⅠ-Ⅱgrade).Results: FIB and PLT of the patiets with breast cancer were higher preoperatively than that postoperatively(P<0.05),APTT obviously decreased postoperatively(P<0.05).Conclusion: Patients with breast cancer in postoperative stage were in hypercoagulabale state(HCS),consequently,deep vein thrombosis(dvt) and lung embolism may develop,prevention and therapy in time are important.

【关键词】 乳腺癌; 高凝状态; 血栓;
【Key words】 breast cancer; hypercoagulabale state; thrombus;
  • 【文献出处】 现代肿瘤医学 ,Journal of Modern Oncology , 编辑部邮箱 ,2010年04期
  • 【分类号】R737.9
  • 【被引频次】5
  • 【下载频次】181
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