【摘要】 目的观察氟达拉宾+阿糖胞苷+粒细胞集落刺激因子方案(FLAG方案)治疗难治及复发性急性髓性白血病的效果。方法采用FLAG方案治疗难治及复发性急性髓性白血病20例。结果完全缓解8例(40%),部分缓解4例(20%),未缓解5例,死亡3例,有效率60%。主要副作用为胃肠道反应和骨髓抑制。结论 FLAG方案治疗难治及复发性急性髓性白血病效果较好。更多还原

【Abstract】 Objective To evaluate combo therapy with fludarabine, cytarabine, and G-CSF (FLAG) for relapsed and refractory acute myeloid leukaemia (AML). Methods The combo therapy of FLAG was applied in the treatment of 20 patients with relapsed and refractory AML. Results Eight (40%) patients achieved complete remission (CR), and four (20%) partial remission, non-remission five, and death three, the effective power being 60%. The main side effects were gastrointestinal tract reactions and bone marrow depression. Conclusion FLAG therapy is effective for relapsed and refractory acute myeloid leukaemia.更多还原