【摘要】 目的研究细胞间粘附分子-1(ICAM-1)与亚临床绒毛膜羊膜炎的关系。方法采用免疫组织化学方法检测ICAM-1在胎膜早破组及相对应孕周末破膜妊娠组(对照组)胎膜中的表达,同时将所有病例的胎膜进行病理组织学检查。结果 ICAM-1在胎膜早破组中的表达明显高于对照组,两者差异有显著意义(P<0.05),而且在发生绒毛膜羊膜炎的研究组中表达更高,两者差异有极显著意义(P<0.01),胎膜早破组中绒毛膜羊膜炎的发生率(64.15%)明显高于对照组(20.00%)。结论细胞间粘附分子-1在胎膜早破组中的表达明显增高,其表达程度与感染程度相关。更多还原

【Abstract】 Objective To study the relationship between intercellular adhesion molecule-1 (CAM-1 ) with subclinical chorioamnionitis.Methods The expression of ICAM-1 in the fetal membrane were detected in premature rupture of membranes group and the corresponding gestational weeks group without membranes rupture (control group ) by immunohistochemisry testing method,while all fetal membranes were examined pathologically.Results The expression of I CAM-1 in premature rupture of membranes group was significantly higher than the control group,and there was a significant difference between two groups (P<0.05),and it show higher expressio in the case of cborioamnionitis in the study group,the difference was significant (P<0.01),the incidence of chorioamnionitis in the premature rupture of membranes group (64.15%) was significantly higher than control group (20.00%).Conclusion There was obviously expression of ICAM-1 in the premature rupture of membranes group and its degree was correlated with the degree of infection.更多还原