【摘要】 以红霉素(EM)为模板分子,甲基丙烯酸甲酯(MAA)为功能单体,制备了红霉素分子印迹聚合物膜。系统研究了EM与MAA用量比、交联剂用量、引发剂种类和用量、洗脱时间等因素对印迹位点及膜分离性能的影响。结果表明,当MAA用量为0.0461mol,EM用量为0.724mmol,交联剂EDMA与MAA摩尔比为5:1,引发剂AIBN与(NH4)2S2O8用量各为0.12g,超声洗脱40min时,膜中印迹位点数多,对红霉素分子的截留率达到55%以上,水通量达70L/(h·m2)以上。更多还原

【Abstract】 Erythromycin molecularly imprinted membranes(EM-MIMs)were prepared by MAA as functional monomer,EDMA as crosslinker in the presence of erythromycin as template.The influences of the proportion of EM and MAA,cross-linking use level,different initiators and use level as well as extraction time on the imprinted sites and specific separation of EM-MIM for EM were investigated.The results show that EM-MIM would obtain more imprinted sites and more excellent separation properties for EM when adding MAA 0.0461 mol,EM 0.724mmol,AIBN and(NH4) 2S2O8 each 0.12g as initiators,and the mole ratio of EDMA to MAA at 5:1.Erythromycin molecules as templates were extracted by ultrasonic oscillating for 40min,using absolute ethyl alcohol as eluant.更多还原