健脾化浊方治疗非酒精性脂肪性肝炎临床研究

【摘要】 目的探讨健脾化浊方治疗非酒精性脂肪性肝炎的临床疗效。方法治疗组40例,口服健脾化浊方,水煎服,每次量约150mL,每日2次;对照组35例,口服多烯磷脂酰胆碱胶囊2粒/次,每日3次,口服。两组疗程均为3个月。两组治疗期间,遵循相同的饮食运动注意事项,并且不用其他保肝、降脂药物。结果治疗组与对照组比较,脘腹胀闷、面色萎黄或白改善率有显著性差异(P<0.01),肝区不适、乏力改善率有显著性差异(P<0.05),总有效率显著提高(P<0.05),治疗组BMI、GGT、肝/脾CT值比值改善较对照组差异有统计学意义(P<0.01)。结论健脾化浊方中药治疗非酒精性脂肪性肝炎疗效显著。更多还原

【Abstract】 Objective To explore the clinical effect of the recipe of invigorating the spleen and eliminating the wetness evil for the treatment of non-alcoholic fatty liver.Methods For the patients in treatment group of 40 cases, take the medicine orally about 150mL each time, twice a day; as for those in the control group, take polyene phosphatidylcholine 2 capsules orally, 3 times a day. During the treatment of 3 months both groups should follow the same diet and direction of exercise without taking other medicines for lowering fat and liver protection. Results In comparison of the two groups, the improvement rate of abdominal distension, nausea, pale complexion has significant difference(P<0.01)and for liver area discomfort and fatigue(P<0.05). The total effective rate increase significantly (P<0.05),The BMI、GGT、Liver/spleen CT value ratio in the treatment group have improved significantly than those in the control group (P<0.01). Conclusion The recipe of invigorating the spleen and eliminating the wetness evil for the treatment of non-alcoholic fatty liver has significant effect.更多还原