【摘要】 目的预防地中海贫血患儿的出生,减少出生缺陷。方法基因诊断采用多聚酶链反应(polymerase chain re-action,PCR)和反向斑点杂交(reverse dot blot,RDB)技术。结果湖北地区84例疑诊患者共检出44例阳性,其中β-地中海贫血为37例。结论湖北地区也应加强地中海贫血的筛查,以减少地中海贫血患儿的出生。更多还原

【Abstract】 Objective:To prevent the birth of thalassemia infant and reduce disfigurement of birth.Methods:Genotyping of thalassemia was performed with polymerase chain reaction and reverse dot blot.Results:44 cases in 84 individuals were found to have thalassemia trait and 37 cases were heterozygous for β-thalassemia.Conclusions:To reduce the birth of thalassemia infant,screening for thalassemia is also should be reinforced in HuBei province.更多还原