【摘要】 目的:探讨急性肺损伤患者血清中肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)、血小板激活因子(Platelet activating factor,PAF)及白细胞介素-10(Interleukin-10,IL-10)的变化及意义。方法:采用ELISA方法检测临床上30例急性肺损伤患者血清中TNF-α、PAF、IL-10不同时间段的浓度变化并进行相关性分析。结果:肺损伤患者血清中TNF-α、PAF、IL-10的水平明显高于对照组。结论:血清TNF-α、PAF、IL-10在肺损伤中起着重要作用。提示这3种指标对肺损伤的诊断、治疗及预后有潜在的应用价值。更多还原

【Abstract】 Objective:To probe the changes of serum and clinical implications of TNF-α(tumor necrosis factors-α) of sera inflammatory cell factors and Interleukin-10(IL-10),PAF in patients with acute lung injury.Methods:The dynamic variations of serum of TNF-α,IL-10, and PAF were tested through ELISA method in 30 strictly chosen patients with acute lung injury and 30 normal people, and relativity analysis was made.Results:There was significant increase levels of TNF-α,IL-10,and PAF in patients with acute lung injury.Conclusion:Serum TNF-α,PAF,IL-10 play an important role in lung injury.This prompts three kinds of indicators have potential application value in diagnosis, treatment and prognosis of lung injury.更多还原