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尘肺患者血清微量元素含量的配对研究

Control Study of Trace Elements in Serum of Patients with Pneumoconiosis

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【作者】 王洪艳陶凌李光浩王嫒丽

【Author】 WANG Hong-yan1,TAO Ling2,LI Guang-hao2,WANG Ai-li2(1.Public Health College of Beihua University,Jilin 132013,China;2.Hospital of Occupational Disease of Jilin City,Jilin 132013,China)

【机构】 北华大学公共卫生学院吉林市职业病防治院

【摘要】 目的探讨微量元素与尘肺病的发生与发展关系,为尘肺病的防治提供依据.方法采用1∶1配对病例对照研究的方法,对40名尘肺患者的血清铜、锌的含量用原子吸收分光光度法进行同步测定.结果尘肺患者血清Cu含量,Cu/Zn明显高于对照组(P<0.05),而血清Zn含量则明显低于对照组(P<0.05).随着尘肺病程和接尘工龄的不同,测试指标均有明显改变.结论血清微量元素铜、锌的含量变化与尘肺病有一定的关系.

【Abstract】 Objective To investigate the relationship between pneumoconiosis and trace elements and provide a basis for prevention and treatment of pneumoconiosis.Method 1 1 matched case control study was carried out.Zinc,Copper in serum of 40 patients with pneumoconiosis were determined at the same time by the atomic absorption spectrometry.Results Cu,Cu / Zn in the serum of patients with pneumoconiosis were significantly higher than those of control group(P<0.05),and Zn in the serum of patients was obviously lower than that of control group(P<0.05).The levels of Cu,Zn showed obvious change with the difference of illness duration and dust-exposed length of service.Conclusion There were some relationships between serum Copper,Zinc content and the incidence of pneumoconiosis.

【关键词】 尘肺病血清微量元素
【Key words】 PneumoconiosisSerumTrace elements
【基金】 吉林市科技发展计划项目(2007057)
  • 【文献出处】 北华大学学报(自然科学版) ,Journal of Beihua University(Natural Science) , 编辑部邮箱 ,2009年05期
  • 【分类号】R135.2
  • 【被引频次】2
  • 【下载频次】69
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