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旋毛虫成囊前期幼虫排泄分泌抗原的研究进展

Progress on excretory-secretory antigens of Trichinella spiralis pre-encysted larva

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【作者】 董明治申丽洁

【Author】 DONG Ming-zhi,SHEN Li-jie (Department of Parasitology,Faculty of Basic Medicine Sciences,Dali University,Dali 671000,Yunnan,China)

【机构】 大理学院基础医学院寄生虫学教研室

【摘要】 在旋毛虫感染过程中,成囊前期幼虫(PEL)是旋毛虫侵入宿主肌肉的侵入期。旋毛虫PEL比成囊期幼虫(EL)在宿主体内约早2周出现。成囊前期幼虫抗原(PELA)对旋毛虫病的早期免疫学诊断具有较高的敏感性。而旋毛虫排泄分泌抗原具双重免疫功能,即有良好的抗原性和免疫原性。因此,本文就旋毛虫成囊前期幼虫ES抗原研究进展做一综述。

【Abstract】 The pre-encysted larvae is the period of invasive hosts muscle in the development of Trichinella spiralis.T.spiralis pre-encysted larvae than encysted larva appeared about two weeks early in hosts.The pre-encysted larva antigens of T.spiralis have high sensitivity in the eary diagnosis of immunization.And excretory-secretory antigen of T.spiralis has double immune function,that is good antigenicity and immunogenicity.Therefore,this article introduced the progress on excretory-secretory antigens of T.spiralis pre-encysted larva.

  • 【文献出处】 中国病原生物学杂志 ,Journal of Pathogen Biology , 编辑部邮箱 ,2009年10期
  • 【分类号】R392
  • 【被引频次】1
  • 【下载频次】177
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