【摘要】 目的调查导管相关性血行感染(CRBSIs)的病原菌分布及药敏情况,为CRBSIs的临床诊治提供参考依据。方法对医院2005年1月-2007年12月中心静脉导管培养阳性的137例病例进行回顾性分析,统计病原菌及污染菌分离情况及主要病原菌药敏结果。结果137例患者中80例为CRBSIs确诊病例,共分离出92株病原菌,革兰阳性球菌43株(46.7%),包括凝固酶阴性葡萄球菌(CNS)31株(33.7%),革兰阴性杆菌31株(33.7%),假丝酵母菌属18株(19.6%);分离病原菌对常用抗菌药物普遍耐药;耐甲氧西林凝固酶阴性葡萄球菌占93.3%,耐甲氧西林金黄色葡萄球菌占75.0%。结论CNS是CRBSIs的最常见病原菌,假丝酵母菌属在CRBSIs的病原菌中占相当比例,常见分离细菌耐药性严重。更多还原

【Abstract】 OBJECTIVE To provide references for clinical diagnosis of catheter-related bloodstream infections(CRBSIs) and focus on studying the spectras of pathogenic bacteria and the drug sensitiveness. METHODS A total of 137 patients enrolled from Jan 2005 to Dec 2007 in our hospital with positive catheter cultures were admitted to our retrospective analysis.Pathogenic bacteria,contaminant bacteria and the drug sensitiveness of main pathogenic bacteria were analyzed. RESULTS From them 80 patients were diagnosed CRBSIs.Among 92 strains of pathogenic bacteria,43(46.7%) strains were Gram-positives,31(33.7%) coagulase negative staphylococci(CNS) strains,31(33.7%) Gram-negative bacilli strains and 18(19.6%) were Candida strains. CONCLUSIONS CNS are the most common bacteria of CRBSIs,and the second are Candida.The common pathogen show multi-drug resistance.更多还原