【摘要】 目的探讨恶性肿瘤患者医院败血症的危险因素。方法对恶性肿瘤医院败血症患者采用1∶2配比的病例对照研究方法,采用单因素及多因素Cox回归分析。结果多因素Cox回归分析显示,糖尿病史(OR=6.864)、原发感染灶(OR=20.189)、中心静脉置管(OR=28.664)、激素使用(OR=8.355)、中性粒细胞<0.5 g/L(OR=12.090)、血白蛋白<35 g/L(OR=3.758),均是恶性肿瘤患者医院败血症发生的危险因素。结论应针对各种危险因素采取有效的预防措施,减少恶性肿瘤患者医院败血症的发生。更多还原

【Abstract】 OBJECTIVE To explore the risk factors of nosocomial sepsis in patients with malignant tumors. METHODS A 1∶2 matched case-control study was designed.The available data were analyzed by monovariant and multivariant Cox regression analysis. RESULTS Multivariant Cox regression analysis showed that diabetes mellitus(OR =6.864),primary infectious focus(OR =20.189),central venous catheterization(OR =28.664),prior glucocorticoid use(OR =8.355),neutrophil<0.5 g/L(OR =12.090) and albumin<35 g/L(OR =3.758) were important risk factors. CONCLUSIONS Effective measures should be taken to prevent nosocomial sepsis in patients with malignant tumors.更多还原