【摘要】 目的考察磷霉素钠与加替沙星氯化钠注射液配伍变化,为临床合理用药提供参考依据。方法在室温条件下观察及测定配伍液8h内的pH及外观变化,并用紫外光谱法监测配伍液中加替沙星的图谱和含量变化。结果两药配伍后,在8h内配伍液的pH及外观无明显变化,而配伍液中加替沙星的紫外图谱和含量均有明显变化。结论磷霉素钠不宜和加替沙星氯化钠注射液配伍使用。更多还原

【Abstract】 Objective To observe the compatibility of fosfomycin sodium with Gatifloxacin and Sodium Chloride Injection,provide reference for clinical rational drug use.Methods At room temperature for 8 hours,the content and UV spectra of fosfomycin sodium with Gatifloxacin and Sodium Chloride Injection were determined by UV spectrophotometry and the change in appearance,pH value were observed.Results There were no evident change in pH value and appearance after the mixture,but the content and UV spectra of the gatifloxacin were changed significantly.Conclusions There exists incompatibility between Fosfomycin Sodium for Injection and and Sodium Chloride Injection.更多还原