【摘要】 目的:了解门诊流动人口支原体感染及耐药情况,为临床治疗用药提供依据。方法:采用支原体培养鉴定药敏检测试剂盒对568例支原体感染患者的标本进行药敏试验。结果:解脲支原体(UU)和人型支原体(MH)阳性总检出率为43.7%(248/568),其中单纯UU阳性率64.5%(160/248),单纯MH阳性率10.1%(25/248),UU+MH混合感染25.4%(63/248)。男性感染率为35.3%(114/248),女性感染率为54.7%(134/248),女性支原体感染率高于男性(P<0.05)。耐药率由高到低分别为环丙沙星(73.8%)、氧氟沙星(68.5%)、大观霉素(32.3%),敏感率由高到低分别为强力霉素(88.3%)、交沙霉素(85.5%)、罗红霉素(80.2%)、克拉霉素(77.4%)和米诺环素(75.4%)。结论:支原体感染是流动人口非淋菌性尿道炎主要病因,支原体耐药性监测对临床合理选择抗菌药物治疗具有重要意义。更多还原

【Abstract】 OBJECTIVE:To study the mycoplasma infection and its drug resistance for reference of clinical treatment.METHODS:A susceptibility test was performed for the specimens of 568 mycoplasma infection cases with the use of susceptibility test kit for culture and identification of mycoplasma.RESULTS:The overall detection rate of ureaplasma urealyticum(UU) and mycoplasma hominis(MH) was 43.7% (248/568),and the detection rates of pure UU,pure MH,and UU plus MH (mixed infection) were 64.5% (160/248),10.1% (25/248),and 25.4% (63/248),respectively.The infection rate of males was cower than that of females [35.3%(114/248) vs.54.7% (134/248),P<0.05].The resistance rates to different drugs ranked in descending order were as follows:ciprofloxacin(73.8%),ofloxacin(68.5%),and spectinomycin(32.3%);and the sensitivity rates to different drugs ranked in descending order were as follows:doxycycline(88.3%),josamycin(85.5%),roxithromycin(80.2%),clarithromycin(77.4%),and minocycline(75.4%).CONCLUSION:Mycoplasma infection is a leading cause of non-gonococcal urethritis of floating population,and monitoring on mycoplasma drug resistance is of significance for clinical rational choice of antibiotics.更多还原